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Published byAnnika Grosse Modified over 5 years ago
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Significance of the principal genetic variants associated with familial pulmonary fibrosis by their strength and frequency. Significance of the principal genetic variants associated with familial pulmonary fibrosis by their strength and frequency. For example, TERT mutations are rare but have a powerful effect with great penetrance, whereas polymorphism of the MUC5B promoter is frequent but with a weaker effect. Modified from [117, 118, 119]. Raphael Borie et al. Eur Respir Rev 2017;26:160122 ©2017 by European Respiratory Society
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