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Intracellular IL-5 and T-lymphocyte subsets in atopic and nonatopic bronchial asthma  Yutaro Shiota, MD, PhDa, Hitomi Arikita, MTa, Naokatsu Horita, MDb,

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Presentation on theme: "Intracellular IL-5 and T-lymphocyte subsets in atopic and nonatopic bronchial asthma  Yutaro Shiota, MD, PhDa, Hitomi Arikita, MTa, Naokatsu Horita, MDb,"— Presentation transcript:

1 Intracellular IL-5 and T-lymphocyte subsets in atopic and nonatopic bronchial asthma 
Yutaro Shiota, MD, PhDa, Hitomi Arikita, MTa, Naokatsu Horita, MDb, Junichiro Hiyama, MD, PhDb, Tetsuya Ono, MD, PhDb, Michio Yamakido, MD, PhDb  Journal of Allergy and Clinical Immunology  Volume 109, Issue 2, Pages (February 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Specificity of staining with PE-conjugated anti-IL-5 antibody (Ab) confirmed by the presence of unconjugated anti-IL-5 antibody (A) or recombinant human IL-5 (B) . Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 IL-5-producing lymphocyte subpopulations from a patient with atopic asthma (A) and a patient with nonatopic asthma (B) . IL-5-producing CD3+ T cells (left panels) , CD4+ T cells (central panels) , and CD8+ T cells (right panels) are shown. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

4 Fig. 3 IL-5-producing CD3+ (left panel) , CD4+ (center panel) , and CD8+ (right panel) T cells in nonatopic healthy subjects (HS) , atopic asthmatic subjects (AA) , and nonatopic asthmatic subjects (NAA) . Horizontal bars indicate median values. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions


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