1. Pipe Cleaner Babies
CLARIFICATION

2. Lab The Pipe cleaners represent the chromosomes
The beads on the pipe cleaners represent alleles (forms of genes)
The pink pipe cleaners are X chromosomes
The blue pipe cleaner is a Y chromosome
Remember humans have 44 autosomes and 2 sex- chromosomes
All females are homologues but males X and Y are not

3. Shows Female and Male Alleles, Genotypes and the key shows phenotypes
Note: All chromosomes are homologous for the female and the male, except the X and Y for the male. The X Y are not homologues and the alleles do not work together.

4. Difference between Autosomal and Sex-linked traits
Questions: Can both the female and male be carriers for blue eyes?
Can both be carriers for hemophilia?

5. Why can women but not men be carriers for sex-linked disorders?
Woman have homologous pairs of X chromosomes that work together with genotype and phenotype
Males have an X and a Y: not
homologous
Thus, no corresponding/matching allele to mask the trait on the X
Look at images from earlier in notes

6. Why do son’s and not daughters inherit a sex-linked trait? (generally)
No corresponding/matching allele for males to mask the trait on the X

7. Comparing hemophilia and sickle cell anemia

8. Autosomal Inheritance (pairs 1-22) Both males and females carriers & Gender inheritance equal
Sex-linked traits (XX and XY)
Only females carriers
Males inherit traits more often
Females inherit mutation from father
What is the difference between sex-linked traits and autosomal trait inheritance?