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Treatment of shiitake dermatitis by balneo PUVA therapy

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Presentation on theme: "Treatment of shiitake dermatitis by balneo PUVA therapy"— Presentation transcript:

1 Treatment of shiitake dermatitis by balneo PUVA therapy
Nina Scheiba, MD, Mindaugas Andrulis, MD, Peter Helmbold, MD  Journal of the American Academy of Dermatology  Volume 65, Issue 2, Pages (August 2011) DOI: /j.jaad Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 A, A 44-year-old male patient with characteristic flagellate dermatitis after ingestion of shiitake. B, Same patient 4 days after balneo PUVA therapy. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Photomicrographs of biopsy specimens before and 3 hours after first PUVA treatment. Hematoxylin-eosin staining shows focally lichenoid and spongiotic, mainly perivascular, superficial and deep dermatitis (A-D). Infiltrate consisted of mainly CD4-positive lymphocytes with some CD8-positive cells (E-H). PUVA therapy induced remarkable reduction of CD207 (langerin)–positive Langerhans cells (I-L). Scale bar: A, B, E-J = 300 μm; C, D = 75 μm; K, L = 150 μm. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2010 American Academy of Dermatology, Inc. Terms and Conditions

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