1. Asthma control can be maintained when fluticasone propionate/salmeterol in a single inhaler is stepped down 
Eric D. Bateman, MD, Loretta Jacques, PhD, Caroline Goldfrad, MSc, Tito Atienza, MD, Triaian Mihaescu, MD, Marie Duggan, BSc 
Journal of Allergy and Clinical Immunology 
Volume 117, Issue 3, Pages (March 2006)
DOI: /j.jaci
Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

2. Fig 1
Study design. Patients were considered eligible for randomization if they fulfilled the criteria for well controlled asthma during each of the last 4 weeks of the open-label period. prn, As needed; b.i.d., twice daily.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

3. Fig 2 Flow of patients in study.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions

4. Fig 3
Percentage of subjects achieving asthma control during each week of the study (ITT population). A, Well controlled asthma. B, Total control of asthma. Only patients who were randomized to double-blind treatment are presented. Includes 53 patients who were randomized even though they had not achieved well-controlled asthma over weeks 9-12 of the open-label phase. bid, Twice daily.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2006 American Academy of Allergy, Asthma and Immunology Terms and Conditions