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IFN-Regulatory Factor 5 Gene Variants Interact with the Class I MHC Locus in the Swedish Psoriasis Population  Fabio O. Sánchez, M.V. Prasad Linga Reddy,

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Presentation on theme: "IFN-Regulatory Factor 5 Gene Variants Interact with the Class I MHC Locus in the Swedish Psoriasis Population  Fabio O. Sánchez, M.V. Prasad Linga Reddy,"— Presentation transcript:

1 IFN-Regulatory Factor 5 Gene Variants Interact with the Class I MHC Locus in the Swedish Psoriasis Population  Fabio O. Sánchez, M.V. Prasad Linga Reddy, Kazuko Sakuraba, Mona Ståhle, Marta E. Alarcón-Riquelme  Journal of Investigative Dermatology  Volume 128, Issue 7, Pages (July 2008) DOI: /sj.jid Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Summary of two-locus genotype combinations between HLA-G_rs16375 and IRF5_rs associated with high risk (quadrants with dark gray background) and low risk. The bar on the left represents the proportion of cases and the bar on the right the proportion of controls. The number of individuals with the corresponding genotype combination in the class case or control appears above each bar. This figure corresponds to the MDR model with the highest consistency and lower misclassification rate (CV consistency=10 of 10; training accuracy=0.57, training OR=1.75, 95% CI=1.3–2.36; testing OR=1.4393, 95% CI=0.58–3.53). Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2008 The Society for Investigative Dermatology, Inc Terms and Conditions


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