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BK virus nephritis after renal transplantation

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Presentation on theme: "BK virus nephritis after renal transplantation"— Presentation transcript:

1 BK virus nephritis after renal transplantation
S. Hariharan  Kidney International  Volume 69, Issue 4, Pages (February 2006) DOI: /sj.ki Copyright © 2006 International Society of Nephrology Terms and Conditions

2 Figure 1 Renal histological findings of interstitial infiltrates and viral cytopathic effects in a case with BKVN. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

3 Figure 2 (a) Evolution of renal function using 100/serum creatinine, illustrating progressive renal failure in a case with BKVN. (b) Evolution of renal function using 100/serum creatinine, illustrating stabilization of renal function in a case with BKVN. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

4 Figure 3 Lower actuarial graft survival rates in patients with BKVN – results from the Medical College of Wisconsin 1996–2004. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

5 Figure 4 Potential pathogenetic mechanisms involved in the occurrence of BKVN from BK viremia. These include sources of BKV infection, molecular viral type, renal tropism, host immunity, and renal transplant ischemic injury prior to engraftment, alloimmune activation, immunosuppression type, and defect in CD40 ligand. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions


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