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Protein nutrition as therapy for a genetic disorder of bone?

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1 Protein nutrition as therapy for a genetic disorder of bone?
T. John Martin  Cell Metabolism  Volume 4, Issue 6, Pages (December 2006) DOI: /j.cmet Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Increased bone formation, bone resorption, and osteoid amount are associated with Nf1 deficiency and/or Atf4 excess Opposite bone effects are associated with deficiency of either Atf4 or Rsk2. Resorption of mineralized bone (gray) by osteoclasts and osteoid synthesis (yellow) by osteoblasts are shown. Protein nutrition affects only the bone formation phenotype. Cell Metabolism 2006 4, DOI: ( /j.cmet ) Copyright © 2006 Elsevier Inc. Terms and Conditions

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