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An XX male with an intratubular undifferentiated germ cell neoplasia
Atilano Carcavilla, M.D., Milagros Alonso, M.D., Ph.D., Begoña Ezquieta, M.D., Ph.D., Eva García-Galloway, Ph.D., Raquel Barrio, M.D., Ph.D., Manuel Nistal, M.D., Ph.D. Fertility and Sterility Volume 90, Issue 5, Pages 2005.e e5 (November 2008) DOI: /j.fertnstert Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions
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Figure 1 (a) Testicular dysgenesis. Anastomizing seminiferous tubules in a poorly collagenized albuginea. (b) Tubular structure in the outer zone of the albuginea resembling a fallopian tube. (Both from testicular biopsy undergone by the age of 5 months.) (c) Intratubular undifferentiated germ cell neoplasia. Large germ cells showing nuclei with irregular outlines and prominent nucleoli. (d) Intratubular undifferentiated germ cell neoplasia. Atypical germ cells showing immunostaining for C-kit. (Both from orchiectomy undergone by the age of 18 years.) (e) SRY probe (red) at the short arm of the deleted X chromosome (green). (f) Location of searched genes/locus on Y chromosome. A = absent; P = present. Fertility and Sterility , 2005.e e5DOI: ( /j.fertnstert ) Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions
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