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Fertility and Sterility

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Presentation on theme: "Fertility and Sterility"— Presentation transcript:

1 Fertility and Sterility
Efficacy of anti-tumor necrosis factor therapy in the treatment of spontaneous endometriosis in baboons  Breton F Barrier, M.D., G.Wright Bates, M.D., M.Michelle Leland, D.V.M., D.Alan Leach, M.D., Randal D Robinson, M.D., Anthony M Propst, M.D.  Fertility and Sterility  Volume 81, Pages (March 2004) DOI: /j.fertnstert

2 FIGURE 1 Pre- and posttreatment lesion surface area in animals treated with either etanercept (brown and light brown bars, n = 7) or vehicle (purple and light purple bars, n = 4). Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility  , DOI: ( /j.fertnstert )

3 FIGURE 2 Percent change in red lesion surface area between first and second laparoscopy in animals treated with etanercept (brown bar) and with placebo (purple bar). Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility  , DOI: ( /j.fertnstert )

4 FIGURE 3 Concentration (trough)-time curves of animals treated with etanercept (n = 7). Each line represents one animal. Only one animal (9490, dark blue diamond) was unable to maintain a measurable serum concentration of etanercept. Barrier. Anti-TNF therapy for endometriosis.Fertil Steril 2004. Fertility and Sterility  , DOI: ( /j.fertnstert )


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