Presentation is loading. Please wait.

Presentation is loading. Please wait.

Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover. Loss of serotonergic markers after Smed-pitx RNAi is not due.

Published byHengki Budiaman Modified over 5 years ago

Similar presentations

Presentation on theme: "Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover. Loss of serotonergic markers after Smed-pitx RNAi is not due."— Presentation transcript:

1 Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover.
Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover. WISH (A-E), FISH (F-J) and immunostainings (F′-J′) are shown. (A) Smed-sert expression in control animals. (B-E) Loss of Smed-sert expression after Smed-pitx RNAi from 1 to 5 dpi (days after the last of three consecutive injections). (F-J) Smed-sert and (F′-J′) SMEDWI-1 expression from 4 to 12 days post-γ-irradiation (dpirr). Note that serotonergic neurons are not affected throughout the timecourse, whereas SMEDWI-1+ stem cell progeny are entirely lost after irradiation (20/20 animals per time point), indicating a relatively slow turnover of serotonergic neurons. Scale bars: 500 μm in A-I′; 250 μm in J,J′. Martin März et al. Development 2013;140: © Published by The Company of Biologists Ltd

Download ppt "Loss of serotonergic markers after Smed-pitx RNAi is not due to stem cell-based turnover. Loss of serotonergic markers after Smed-pitx RNAi is not due."

Similar presentations

Effect of miR-29a inhibition on miRNA and SCD expression in GIFT

Effect of miR-29a inhibition on miRNA and SCD expression in GIFT
inhibits BMP signalling.

inhibits BMP signalling.
Mitochondria localize to both the front and the rear of neutrophils.

Mitochondria localize to both the front and the rear of neutrophils.
Identification of vegetally localised vrtn transcripts.

Identification of vegetally localised vrtn transcripts.
H1‐NPCs differentiate into TH+ midbrain DA neurons with high efficiency. H1‐NPCs differentiate into TH+ midbrain DA neurons with high efficiency. (A) MAP2‐expressing.

H1‐NPCs differentiate into TH+ midbrain DA neurons with high efficiency. H1‐NPCs differentiate into TH+ midbrain DA neurons with high efficiency. (A) MAP2‐expressing.
Scanning electron microscopy analysis of EGK-I to -V chick embryos.

Scanning electron microscopy analysis of EGK-I to -V chick embryos.
KIN-3 depletion leads to increased levels of centrosomal ZYG-1

KIN-3 depletion leads to increased levels of centrosomal ZYG-1
Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.

Fig. 8. CCA and ChQ treatment induce accumulation of F-actin rings.
BTN1 mRNA level in response to extracellular pH determined by comparative RT2PCR. BTN1mRNA level in response to extracellular pH determined by comparative.

BTN1 mRNA level in response to extracellular pH determined by comparative RT2PCR. BTN1mRNA level in response to extracellular pH determined by comparative.
Differential Cre-ERT activity and PTEN deletion in endometrial epithelial and stromal compartments. Differential Cre-ERT activity and PTEN deletion in.

Differential Cre-ERT activity and PTEN deletion in endometrial epithelial and stromal compartments. Differential Cre-ERT activity and PTEN deletion in.
Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.

Fig. 7. Motion adaptation increases time-dependent response modulations (TDRM) relatively to the average cell response.TDRM normalized to the value obtained.
Localisation of epithelial markers in mMEC cultures.

Localisation of epithelial markers in mMEC cultures.
A highly conserved six-amino-acid region in the C-terminal CT domain of MARCH8 is responsible for its ability to downregulate TfR. A highly conserved six-amino-acid.

A highly conserved six-amino-acid region in the C-terminal CT domain of MARCH8 is responsible for its ability to downregulate TfR. A highly conserved six-amino-acid.
Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.

Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.
Fig. 3. Knockdown of cited3 results in increased cell death but it does not affect proliferation.Embryos that are injected with the control MO (A–C), cited3.

Fig. 3. Knockdown of cited3 results in increased cell death but it does not affect proliferation.Embryos that are injected with the control MO (A–C), cited3.
Fig. 7. Knockdown of Meis1 abolishes CR4. 2-GFP expression

Fig. 7. Knockdown of Meis1 abolishes CR4. 2-GFP expression
Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.
Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos at E12.5. Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos.

Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos at E12.5. Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos.
Fig. 1. Morphological and growth characterization of hBMCs and hPDCs

Fig. 1. Morphological and growth characterization of hBMCs and hPDCs
Ectopic sprouting and proliferation in Rbpj veins.

Ectopic sprouting and proliferation in Rbpj veins.

Similar presentations

Ads by Google