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Fig. 3. Reduced histone H3K9 trimethylation in SCNT embryos treated with TSA and VC. (A) Immunostaining analysis indicated that SCNT embryos with TSA+VC.

Published byΒηθζαθά Παπαδόπουλος Modified over 5 years ago

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Presentation on theme: "Fig. 3. Reduced histone H3K9 trimethylation in SCNT embryos treated with TSA and VC. (A) Immunostaining analysis indicated that SCNT embryos with TSA+VC."— Presentation transcript:

1 Fig. 3. Reduced histone H3K9 trimethylation in SCNT embryos treated with TSA and VC. (A) Immunostaining analysis indicated that SCNT embryos with TSA+VC showed a significantly lower level of H3K9me3 compared to control embryos. Reduced histone H3K9 trimethylation in SCNT embryos treated with TSA and VC. (A) Immunostaining analysis indicated that SCNT embryos with TSA+VC showed a significantly lower level of H3K9me3 compared to control embryos. Different letters indicate statistical significance (P<0.05, one-way ANOVA with subsequent Tukey's multiple comparison tests). Fourteen or fifteen two-cell embryos were examined. Error bars represent means±s.e. (n=3). (B) A model shows how the treatment with trichostatin A and vitamin C in the dBSA-containing medium enhances epigenetic reprogramming and results in the enhanced cloning success rate. Kei Miyamoto et al. Biology Open 2017;6: © Published by The Company of Biologists Ltd

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