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Proteasome Inhibition and Allogeneic Hematopoietic Stem Cell Transplantation: A Review
John Koreth, Edwin P. Alyea, William J. Murphy, Lisbeth A. Welniak Biology of Blood and Marrow Transplantation Volume 15, Issue 12, Pages (December 2009) DOI: /j.bbmt Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions
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Figure 1 Potential mode of action in bortezomib mediated antitumor responses. Bortezomib may have a negative impact on the growth and spread of cancer cells through multiple mechanisms including direct induction of apoptosis, sensitization to killing by CD8+ cytotoxic T cells and NK cells, and through reduction of inflammation resulting in decreased metastasis. Biology of Blood and Marrow Transplantation , DOI: ( /j.bbmt ) Copyright © 2009 American Society for Blood and Marrow Transplantation Terms and Conditions
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