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Published byIndra Cahyadi Modified over 5 years ago
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Use of a mixed endothelin receptor antagonist in portopulmonary hypertension: A safe and effective therapy? Christian Kuntzen, Veit Gülberg, Alexander L. Gerbes Gastroenterology Volume 128, Issue 1, Pages (January 2005) DOI: /j.gastro Copyright © 2005 American Gastroenterological Association Terms and Conditions
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Figure 1 Time course of cardiopulmonary function parameters obtained before and during bosentan therapy. Therapy was started in June 2002 with 62.5 mg twice daily. The dose was doubled in October 2002 (month 5) and has been kept constant since then. (A) Cardiac catheterization. PVR, pulmonary vascular resistance; CI, cardiac index; mPAP, mean pulmonary artery pressure. (B) Plasma BNP concentration (normal range <18 pg/mL). (C) Six-minute walk test was performed under standardized conditions. Gastroenterology , DOI: ( /j.gastro ) Copyright © 2005 American Gastroenterological Association Terms and Conditions
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