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GENE MUTATIONS (in DNA)

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Presentation on theme: "GENE MUTATIONS (in DNA)"— Presentation transcript:

1 GENE MUTATIONS (in DNA)
GENE MUTATIONS (in DNA)

2 Point Mutations Happen At Single Nucleotide Points in DNA
Point Mutations Happen At Single Nucleotide Points in DNA Substitution One base changes to (“subs” for) another Insertion Base added (inserted) Deletion Base removed (deleted)

3 The Dog Ate The Fat Cat Substitution Deletion Insertion
The Dog Ate The Fat Rat Deletion The Oga Tet Hef Atr At.. Insertion The Dog Tat Eth Efa Tra t

4 What kind of point mutation?
SUBSTITUTION

5 What kinds of point mutation?
INSERTION DELETION

6 Insertions and Deletions Can Cause FRAMESHIFTS in the code!
Insertions and Deletions Can Cause FRAMESHIFTS in the code! One nucleotide affected every codon down the line—a frameshift!

7 CHROMOSOMAL MUTATIONS (affect whole chromosomes)
CHROMOSOMAL MUTATIONS (affect whole chromosomes)

8 What Would You Call It? Deletion

9 One or more segment is repeated
What Would You Call It? normal chromosome one segment repeated three repeats Duplication One or more segment is repeated

10 A linear stretch of DNA is reversed within the chromosome
What Would You Call It? Inversion A linear stretch of DNA is reversed within the chromosome

11 What Would You Call It? chromosome nonhomologous chromosome reciprocal translocation Translocation Entire gene segments are exchanged between non-homologous chromosomes!

12 Check Point

13 Mutations may be:  Silent or neutral (no effect)
Harmful or Fatal (bad effect) Beneficial (good effect, low probability)


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