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The mutants exhibit congenital hypothyroidism.

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Presentation on theme: "The mutants exhibit congenital hypothyroidism."— Presentation transcript:

1 The mutants exhibit congenital hypothyroidism.
The mutants exhibit congenital hypothyroidism. (A) The mutation was located in the peroxidase-like domain. (B) Histological section analysis indicated abnormalities in the thyroid and pituitary glands, which are associated with thyroid hormone production. Scale bars: 50 μm. (C) Measurement of thyroid hormones in the peripheral blood showed that the thyroid hormones of T3 and T4 were significantly decreased in mutant pigs, whereas TSH was markedly elevated (mean±s.d.; Student's t-test; **P<0.01; n=6 in each group). AA, amino acids. Chunwei Cao et al. Dis. Model. Mech. 2019;12:dmm036616 © Published by The Company of Biologists Ltd

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