1. Perspectives on hormone replacement therapy: the Women's Health Initiative and new observational studies sampling the overall population 
Richard L. Tannen, M.D., Mark G. Weiner, M.D., Dawei Xie, Ph.D., Kurt Barnhart, M.D., M.S.C.E. 
Fertility and Sterility 
Volume 90, Issue 2, Pages (August 2008)
DOI: /j.fertnstert
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Comparison of the response to hormone replacement therapy (HRT) between the Women's Health Initiative randomized, controlled trial (WHI RCT) and our population studies. The response of women with an intact uterus treated with combined HT is shown in the left panel, and those with a prior hysterectomy treated with estrogen only is shown on the right. The data for each outcome are grouped with the response of older women in the upper and younger women in the lower portion. Abbreviations: CHD, coronary heart disease in WHI RCT or myocardial infarction only in United Kingdom General Practice Research Database (GPRD) studies; CVA, cerebrovascular accident. The legend defines the age of the study group. Cox adjusted hazard ratios (HR) are shown for all data except those labeled Prior Event Rate Ratio (PERR), which were analyzed with this adjustment. “No missing” in the death analysis refers to a subset of the cohort who were not missing any data on the potential confounders (blood pressure, body mass index, and smoking).
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions