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Fig. 3. Electron micrographs showing presynaptic autophagosomes in hippocampal neurons treated with ShhN.(A–D,F) Examples of early autophagosomes (avi).

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Presentation on theme: "Fig. 3. Electron micrographs showing presynaptic autophagosomes in hippocampal neurons treated with ShhN.(A–D,F) Examples of early autophagosomes (avi)."— Presentation transcript:

1 Fig. 3. Electron micrographs showing presynaptic autophagosomes in hippocampal neurons treated with ShhN.(A–D,F) Examples of early autophagosomes (avi). Electron micrographs showing presynaptic autophagosomes in hippocampal neurons treated with ShhN.(A–D,F) Examples of early autophagosomes (avi). (D) A synapse with a presynatic terminal (p) and a postsynaptic spine (s). Above this typical synapse, a large process is almost completely occupied by autophagosomes resulting in a few barely visible obscured vesicles. (E) An example of a late autophagosome (avd) based on the characteristic osmiophilic contents. Scale bar: 100 nm. (G) Quantification of presynaptic terminals that contain a multivesicular body or autophagosome. n = 229 presynaptic terminals for control; n = 229 presynaptic terminals for ShhN-treated. Ronald S. Petralia et al. Biology Open 2013;2: © Published by The Company of Biologists Ltd

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