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Jeffrey Y. Lin, MD, Petar Igic, MD, FHRS, Kurt S

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1 Patients with hemophilia: Unique challenges for atrial fibrillation management 
Jeffrey Y. Lin, MD, Petar Igic, MD, FHRS, Kurt S. Hoffmayer, MD, PharmD, FHRS, Michael E. Field, MD, FHRS  HeartRhythm Case Reports  Volume 1, Issue 6, Pages (November 2015) DOI: /j.hrcr Copyright © 2015 Heart Rhythm Society Terms and Conditions

2 Figure 1 Proposed algorithm for management of antithrombotic therapy in patients with hemophilia and atrial fibrillation. Note that anticoagulation is not recommended unless the basal factor level is ≥30%. Adapted from Mannucci et al (2009).2 HeartRhythm Case Reports 2015 1, DOI: ( /j.hrcr ) Copyright © 2015 Heart Rhythm Society Terms and Conditions

3 Figure 2 The coagulation cascade and primary targets of commonly used anticoagulants in the management of atrial fibrillation and sites of deficiency in patients with hemophilia A and B. HeartRhythm Case Reports 2015 1, DOI: ( /j.hrcr ) Copyright © 2015 Heart Rhythm Society Terms and Conditions

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