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Methasteron-Associated Cholestatic Liver Injury: Clinicopathologic Findings in 5 Cases  Neeral L. Shah, Isabel Zacharias, Urmila Khettry, Nezam Afdhal,

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1 Methasteron-Associated Cholestatic Liver Injury: Clinicopathologic Findings in 5 Cases 
Neeral L. Shah, Isabel Zacharias, Urmila Khettry, Nezam Afdhal, Fredric D. Gordon  Clinical Gastroenterology and Hepatology  Volume 6, Issue 2, Pages (February 2008) DOI: /j.cgh Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 Medium-power photomicrograph of the liver biopsy specimen depicting intact lobular architecture. There is prominent intrahepatocytic and intracanalicular cholestasis involving the centrilobular area (zone 3). There is minimal portal chronic inflammation without any biliary epithelial injury. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Structural comparison of oxymetholone, drostanolone, and estrogen with methasteron (arrows indicate difference in structure). Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions


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