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2007 Annual Meeting of the National Lung Cancer Partnership: A Summary of Meeting Highlights
Regina M. Vidaver, PhD, Beth S. Schachter, PhD Journal of Thoracic Oncology Volume 3, Issue 2, Pages (February 2008) DOI: /JTO.0b013e c43 Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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FIGURE 1 Combining MEK and mTOR inhibitors in lung cancer. Components of the RAS-AKT signaling network converge at many levels to control translation, mitogenesis, differentiation, and senescence. The mTOR inhibitor rapamycin and the MEK inhibitor PD (a derivative of CI-1040) act synergistically to inhibit cell proliferation in human lung cancer cell lines. Journal of Thoracic Oncology 2008 3, DOI: ( /JTO.0b013e c43) Copyright © 2008 International Association for the Study of Lung Cancer Terms and Conditions
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