1. Role of neuropeptide Y in the development of two-kidney, one-clip renovascular hypertension in the rat 
Lynn H. Shin, MD, Peter S. Dovgan, MD, Timothy J. Nypaver, MD, Oscar A. Carretero, MD, William H. Beierwaltes, PhD, 
Journal of Vascular Surgery 
Volume 32, Issue 5, Pages (November 2000)
DOI: /mva
Copyright © 2000 Society for Vascular Surgery and The American Association for Vascular Surgery, a Chapter of the International Society for Cardiovascular Surgery Terms and Conditions

2. Fig. 1
A, Effect of NPY on MAP in anesthetized rats, before and after administration of Y-1 antagonist BIBO3304TF. BIBO3304TF significantly attenuated the pressor response to NPY (n = 5; P <.02). B, Effect of NPY on RBF in anesthetized rats, before and after attenuation with Y-1 antagonist BIBO3304TF. BIBO3304TF significantly attenuated the vasoconstrictive response to NPY (n = 5; P <.05).
Journal of Vascular Surgery  , DOI: ( /mva )
Copyright © 2000 Society for Vascular Surgery and The American Association for Vascular Surgery, a Chapter of the International Society for Cardiovascular Surgery Terms and Conditions

3. Fig. 2
Effect of chronic administration of BIBO3304TF on development of 2K1C RVH. SBP is 26 mm Hg lower in BIBO3304TF-treated rats (dashed line) than in clipped controls (P <.01).
Journal of Vascular Surgery  , DOI: ( /mva )
Copyright © 2000 Society for Vascular Surgery and The American Association for Vascular Surgery, a Chapter of the International Society for Cardiovascular Surgery Terms and Conditions

4. Fig. 3
Effect of NPY on iso-stimulated renin release from renal cortical slices. Iso significantly increased renin release (P <.01); however, no significant effect of NPY on stimulated renin release was demonstrated (P =.09).
Journal of Vascular Surgery  , DOI: ( /mva )
Copyright © 2000 Society for Vascular Surgery and The American Association for Vascular Surgery, a Chapter of the International Society for Cardiovascular Surgery Terms and Conditions