1. Fig. 1 ZIKV RNA in blood and tissues.
ZIKV RNA in blood and tissues. (A) Plasma ZIKV RNA concentration as measured by RT-PCR. (B) Assessment of ZIKV RNA concentration by RT-PCR in lymphoid (top) and nonlymphoid tissues (bottom) at day 3 or days 14 and 15 post-infection (p.i.). Low RNA indicates that <20 ng/μl was run in the PCR. LN, lymph node. (C) Representative detection of ZIKV RNA by RNAscope in situ hybridization in nervous system tissues. Arrowheads indicate some of the most intense RNAscope signals (red). No arrowheads were placed on the bottom left panel because the RNAscope signal was diffusely positive in the cerebellum at this magnification. Scale bars, 100 μm (left panels) and 50 μm (right panels). Four to five images per brain area were examined.
Maud Mavigner et al., Sci Transl Med 2018;10:eaao6975
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