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Sara C. Meyer, Alix O’Meara, Andreas S. Buser, André Tichelli, Jakob R

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Presentation on theme: "Sara C. Meyer, Alix O’Meara, Andreas S. Buser, André Tichelli, Jakob R"— Presentation transcript:

1 Prognostic Impact of Posttransplantation Iron Overload after Allogeneic Stem Cell Transplantation 
Sara C. Meyer, Alix O’Meara, Andreas S. Buser, André Tichelli, Jakob R. Passweg, Martin Stern  Biology of Blood and Marrow Transplantation  Volume 19, Issue 3, Pages (March 2013) DOI: /j.bbmt Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Time course of complete iron parameters before and after HSCT. Ferritin (μg/L), transferrin saturation (%), plasma iron (μmol/L), transferrin (g/L), and the soluble transferrin receptor (sTfR) (mg/L) were serially measured in patients undergoing allogeneic HSCT after myeloablative conditioning. Values are presented before starting the conditioning chemotherapy preparing for HSCT as well as 1, 3, 6, 12, 24, 36, and 60 months after allogeneic HSCT. The curve indicates the median at the respective time points. Interquartile ranges (IQRs) are indicated by bars. Gray areas represent healthy donor normal ranges. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 Time-stratified Kaplan-Meier survival analysis for ferritin. Patients were categorized according to ferritin values below (dotted line) or above (continuous line) median. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Time-stratified cumulative incidence of relapse and transplantation-related mortality. Patients were categorized according to ferritin values below (dotted line) or above (continuous line) median. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2013 American Society for Blood and Marrow Transplantation Terms and Conditions


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