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2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft. 2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft.

Published byMark Lyons Modified over 5 years ago

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Presentation on theme: "2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft. 2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft."— Presentation transcript:

1 2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft.
2DG downregulates the expression of HIF-1α, PDK1 and c-Myc in NB xenograft. The mice received subcutaneous injection of SK-N-DZ NB cells (A,B) and SK-N-AS NB cells (C-E) and received a total of six doses of normal saline or 2DG. The xenografts were harvested on the 27th day and then subjected to western blotting using the indicated antibodies. Graph data are the means±s.e.m.; *P<0.05. n=4 (A,C,E); n=7 for normal saline group and n=4 for 2DG groups (B); and n=7 (D). Chao-Cheng Huang et al. Dis. Model. Mech. 2015;8: © Published by The Company of Biologists Ltd

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