1. Exogenous CRP administration causes fasting hyperglycemia and hyperinsulinemia without altering body composition.
Exogenous CRP administration causes fasting hyperglycemia and hyperinsulinemia without altering body composition. Wild-type mice were intraperitoneally injected with vehicle or CRP every other day for 14 days. On days 0 and 15, fasting plasma levels of glucose (A) and insulin (B), body weight (C), fat mass (D), and lean mass (E) were measured. Values are mean ± SEM, n = 7–14. *P < 0.05 vs. vehicle.
Keiji Tanigaki et al. Diabetes 2013;62:
©2013 by American Diabetes Association