1. Gene expression in islets isolated from diabetic mice.
Gene expression in islets isolated from diabetic mice. Real-time RT-PCR analysis of mRNA expression of insulin I (A), insulin II (B), Pdx-1 (C), LC3 (D), DNAJC3 (E), and PCNA (F). Results were standardized to β-actin mRNA levels and then expressed as fold changes vs. the lean-PBS mice. Data are mean ± SEM. n = 3 animals/group. *P < 0.05, **P < 0.01, ***P < vs. the lean-PBS group; +P < 0.05, ++P < 0.01, +++P < vs. the db/db-PBS group.
Yi Lin, and Zhongjie Sun Diabetes 2015;64:
©2015 by American Diabetes Association