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RIPK3 Slams the Brake on Leukemogenesis

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Presentation on theme: "RIPK3 Slams the Brake on Leukemogenesis"— Presentation transcript:

1 RIPK3 Slams the Brake on Leukemogenesis
Francis Ka-Ming Chan  Cancer Cell  Volume 30, Issue 1, Pages 7-9 (July 2016) DOI: /j.ccell Copyright © 2016 Elsevier Inc. Terms and Conditions

2 Figure 1 RIPK3 and MLKL Mediate Cell Death and IL-1β Processing to Limit the Extent of FLT3-ITD-Induced Leukemogenesis In human AML, loss of RIPK3 and MLKL inhibit these processes, which results in a developmental block and enhanced survival of transformed immature progenitors. Cancer Cell  , 7-9DOI: ( /j.ccell ) Copyright © 2016 Elsevier Inc. Terms and Conditions

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