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Fig. 4 Mutations and reduced expression of human KDM6A predict poor prognosis of female patients with BCa. Mutations and reduced expression of human KDM6A predict poor prognosis of female patients with BCa. (A and B) Outlier box plot of KDM6A gene expression in BCa samples from males and females (A) and from different cancer stages (B). Student’s t test. (C and D) KDM6A mutations (C) and decreased expression (D) correlate tightly to poor disease-free survival of female but not of male patients with BCa. Kaplan-Meier analysis, log-rank test. Satoshi Kaneko, and Xue Li Sci Adv 2018;4:eaar5598 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).
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