1. Isotretinoin treatment for acne and risk of depression: A systematic review and meta- analysis 
Yu-Chen Huang, MD, Ying-Chih Cheng, MD 
Journal of the American Academy of Dermatology 
Volume 76, Issue 6, Pages e9 (June 2017)
DOI: /j.jaad
Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

2. Fig 1
Selection of studies included in the present systematic review and meta-analysis.
Journal of the American Academy of Dermatology  , e9DOI: ( /j.jaad )
Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

3. Fig 2
Forest plot. Standardized mean difference in depression score change from baseline (post-score minus pre-score) between the isotretinoin group and the control group (isotretinoin group minus control group). The more negative a standardized mean difference is the greater the improvement in depression scores in the isotretinoin group in comparison with the control group.
Journal of the American Academy of Dermatology  , e9DOI: ( /j.jaad )
Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions

4. Fig 3
Funnel plot analysis for potential publication bias. The funnel plot for change in depression scores in 19 studies showed no asymmetry, which means no publication bias. Each dot represents a study; the y-axis represents the standard error of the study and the x-axis shows the study result (standardized mean difference of pre- and post-treatment depression scores in each study).
Journal of the American Academy of Dermatology  , e9DOI: ( /j.jaad )
Copyright © 2016 American Academy of Dermatology, Inc. Terms and Conditions