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Pentoxifylline ameliorates proteinuria through suppression of renal monocyte chemoattractant protein-1 in patients with proteinuric primary glomerular.

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Presentation on theme: "Pentoxifylline ameliorates proteinuria through suppression of renal monocyte chemoattractant protein-1 in patients with proteinuric primary glomerular."— Presentation transcript:

1 Pentoxifylline ameliorates proteinuria through suppression of renal monocyte chemoattractant protein-1 in patients with proteinuric primary glomerular diseases  Y.-M. Chen, S.-L. Lin, W.-C. Chiang, K.-D. Wu, T.-J. Tsai  Kidney International  Volume 69, Issue 8, Pages (April 2006) DOI: /sj.ki Copyright © 2006 International Society of Nephrology Terms and Conditions

2 Figure 1 Single-voided (left panel) and 24-h (right panel) urinary protein/Cr ratios in the studied patients before and after PTX therapy. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

3 Figure 2 Changes of urinary cytokines before and after PTX therapy.
Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

4 Figure 3 The correlation between percent reduction of urinary protein/Cr ratios and percent reduction of urinary MCP-1/Cr ratios after PTX therapy. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions

5 Figure 4 Changes of renal function in the studied patients before and after PTX therapy. Black circles represent the two patients with IgA nephropathy exhibiting deterioration of renal function. GFR denotes glomerular filtration rates. Kidney International  , DOI: ( /sj.ki ) Copyright © 2006 International Society of Nephrology Terms and Conditions


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