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Volume 44, Issue 2, Pages (February 2006)

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Presentation on theme: "Volume 44, Issue 2, Pages (February 2006)"— Presentation transcript:

1 Volume 44, Issue 2, Pages 407-410 (February 2006)
Chronic liver disease related to 6-thioguanine in children with acute lymphoblastic leukaemia  Ruth De Bruyne, Bernard Portmann, Marianne Samyn, Sanjay Bansal, Alex Knisely, Giorgina Mieli-Vergani, Anil Dhawan  Journal of Hepatology  Volume 44, Issue 2, Pages (February 2006) DOI: /j.jhep Copyright © Terms and Conditions

2 Fig. 1 Liver histology showing bridging areas of sinusoidal dilatation with concomitant plate atrophy (arrowed) alternating with regenerative parenchyma. Note early reticulin collagenisation (gold-brown in B) and early nodule formation. (*) Hematoxylin-eosin (a) and reticulin (b) staining. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © Terms and Conditions

3 Fig. 2 Liver histology showing a semingly more advanced stage of disease with marked architectural distortion and some fibrosis. There is a subtle ductular reaction and a dilated inlet venule (IV) bulging out of the portal area. Hematoxylin-eosin (a) and reticulin (b) staining. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © Terms and Conditions

4 Fig. 3 Liver histology showing ground-glassy ‘Lafora-like’ inclusion bodies which are arrowed. Hematoxylin-eosin staining. [This figure appears in colour on the web.] Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © Terms and Conditions


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