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GSIS. GSIS. In vivo: serum insulin levels at fasting state and 30 min after glucose injection (A) and the fold change in serum insulin after glucose loading.

Published byDanuta Sawicka Modified over 5 years ago

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Presentation on theme: "GSIS. GSIS. In vivo: serum insulin levels at fasting state and 30 min after glucose injection (A) and the fold change in serum insulin after glucose loading."— Presentation transcript:

1 GSIS. GSIS. In vivo: serum insulin levels at fasting state and 30 min after glucose injection (A) and the fold change in serum insulin after glucose loading (B) in male offspring (nCtrl-F1_NCD = 7, nINS-F1_NCD = 7, nGDM-F1_NCD = 7, nCtrl-F1_HFD = 7, nINS-F1_HFD = 9, nGDM-F1_HFD = 12). Serum insulin levels at fasting state and 30 min after glucose injection (C) and the fold change in serum insulin after glucose loading (D) in female offspring (nCtrl-F1_NCD = 7, nINS-F1_NCD = 8, nGDM-F1_NCD = 10, nCtrl-F1_HFD = 6, nINS-F1_HFD = 6, nGDM-F1_HFD = 7). E: In vitro GSIS in isolated islets from 20-week-old male offspring (n = 5 mice per group). F: GSIS in isolated islets from 20-week-old female offspring (n = 5 mice per group). Data are expressed as mean ± SEM. *P < 0.05 vs. Ctrl-F1, **P < 0.01 vs. Ctrl-F1. #P < 0.05 vs. INS-F1; ##P < 0.01 vs. INS-F1 (ANOVA). Hong Zhu et al. Diabetes 2019;68: ©2019 by American Diabetes Association

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