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Urine pH in different disorders.

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1 Urine pH in different disorders.
Urine pH in different disorders. Acidification of the urine in controls after an acute acid load results in a urine pH <5.5 (dotted line). Similarly, urine pH will be <5.5 in patients with CKD, those with low aldosterone states, and PRTA when the serum [HCO3−] is below the reabsorptive threshold. By contrast, it will be >5.5 in patients with DRTA, those with tubular resistance to aldosterone, and those with PRTA when the serum [HCO3−] is above the reabsorptive threshold. THD, reabsorptive threshold; C, controls; DRTA, distal RTA; aldo, aldosterone; tub. res, tubular resistance; PRTA, proximal RTA. Jeffrey A. Kraut, and Nicolaos E. Madias CJASN 2012;7: ©2012 by American Society of Nephrology

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