1. Discrimination of site-specific alterations in gastrointestinal permeability in the rat 
Jon B. Meddings, Ian Gibbons 
Gastroenterology 
Volume 114, Issue 1, Pages (January 1998)
DOI: /S (98)
Copyright © 1998 American Gastroenterological Association Terms and Conditions

2. Fig. 1
Aspirin-induced damage. Data are reported as the mean ± SEM determined from at least 10 animals. (A) Fractional excretion of sucrose. (B) Lactulose-mannitol ratio. (C) Fractional excretion of sucralose. 2, Control animals; ▩, low-dose aspirin; ■, high-dose aspirin. Fractional excretion rates of sucrose are increased with either dose of aspirin and the lactulose-mannitol ratio by high-dose aspirin. Sucralose excretion rates were unaffected by aspirin. *P < 0.05 vs. controls.
Gastroenterology  , 83-92DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

3. Fig. 2
Indomethacin-induced damage. The format for this figure is identical to that of Figure 1. Indomethacin (Indo) significantly increased both sucrose permeability and the lactulose-mannitol ratio. High-dose indomethacin also significantly increased the fractional excretion of sucralose. *P < 0.05 vs. controls. **P < 0.05 high-dose indomethacin vs. low-dose indomethacin and controls.
Gastroenterology  , 83-92DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

4. Fig. 3
TNBS colitis. The format for this figure is identical to that of Figure 1. The only probe significantly affected by the presence of colitis was sucralose. *P < 0.05 vs. controls.
Gastroenterology  , 83-92DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

5. Fig. 4
Sucrose-lactulose ratios. Sucrose-lactulose ratios for all experimental groups are presented. The significance of this measurement is discussed more completely in the text. Indo, indomethacin. *P < 0.05 vs. controls.
Gastroenterology  , 83-92DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions

6. Fig. 5
Lactulose-sucralose ratios. Lactulose-sucralose ratios for all experimental groups are presented. The significance of these data is discussed more extensively in the text. Indo, indomethacin. *P < 0.05 vs. controls.
Gastroenterology  , 83-92DOI: ( /S (98) )
Copyright © 1998 American Gastroenterological Association Terms and Conditions