1. RADIOBIOLOGY OF THE EYE LENS
Session 10: Regulatory Implications and relevance of revised dose limits to the eye
Speaker Details: Prof John Akudugu (University of Stellenbosch)

2. Markiewicz et al. 2015, Open Biology 5: 150011.
2nd NUCLEAR REGULATORY INFORMATION CONFERENCE
Germinative zone
Transition zone +
Meridional rows
Peripheral region
Markiewicz et al. 2015, Open Biology 5:

3. 2nd NUCLEAR REGULATORY INFORMATION CONFERENCE
Peripheral region
Eye lens epithelial cell DNA repair capacity: H2AX disappearance
Differences in DNA repair rate
Increased proliferation of cells in peripheral region
Increased aspect ratios ( some distortion in vision)

4. Akudugu et al. 2004, Radiotherapy and Oncology 72: 103-112.
2nd NUCLEAR REGULATORY INFORMATION CONFERENCE
Akudugu et al. 2004, Radiotherapy and Oncology 72:
Skin fibroblast proliferation vs wound healing complication (WHC) & fibrosis in soft tissue sarcoma patient treated with preoperative radiotherapy
Fibroblasts from patients with WHC/fibrosis showed increased proliferation after radiation exposure