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Waddington’s Valleys and Captain Cook’s Islands

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1 Waddington’s Valleys and Captain Cook’s Islands
Michael H. Sieweke  Cell Stem Cell  Volume 16, Issue 1, Pages 7-8 (January 2015) DOI: /j.stem Copyright © 2015 Elsevier Inc. Terms and Conditions

2 Figure 1 Waddington’s and Cook’s Reprogramming Landscapes
Alternative models of Waddington’s (A) and Cook’s (B) reprogramming landscapes showing mature cell types (a, b, and c) and intermediate states (1, 2, 3) of cellular development. Lines in (B) retrace a hypothetical Polynesian settlement of French Polynesia from west to east (red) and Captain Cook’s route from east to west (blue) as models of development and reprograming, respectively. Cell Stem Cell  , 7-8DOI: ( /j.stem ) Copyright © 2015 Elsevier Inc. Terms and Conditions

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