1. Evidence for Human Variation and Adaption
Venessa Williams
Hai Tran
Myles Everett
Alex Detlefsen
Bio 1510-A Group A39
September 13, 2012

2. Introduction Little known about genome sequences of Africans
Common ancestors
1000 Genomes Project used new technology to view whole genome sequences
Shared traits
Local genetic adaptions
Natural selections
All humans originate from a common ancestor native to Africa.
1000 Genomes Project used new technology developed to view whole genome sequences of various African tribes to examine the origins of modern humans and understand the spectrum of human genetic diversity.
Although the three different tribes that were tested share some common characteristics, there are genetic differences due to adaptions to their different environments and natural selection.

3. Data/Results
15 African hunter-gathers complete genetic sequences gathered
13,407,517 variants found (5 million new)
37,797 nonsynomolous and 35,747 synomolous
50% traits shared among three groups
Genomic regions that contain a large number of variants in one population also contain a large number of variants in other populations.
Homozygosity (introgression)

5. Discussion Not an excess of shared characteristics Natural Selection
Ancestral divergence
Gene flow
Local adaption
Natural Selection
Unknown Hominin ancestor
Bottlenecking and migration

6. Conclusion
Whole human genome sequencing can help determine factors of genetic diversity and unravel the origins of human life.

7. Literature Cited
Tishkoff, Sarah. "Whole-genome Sequencing of Africa's Hunter-gatherers Elucidates Human Variation and Ancient Interbreeding." Whole-genome Sequencing of Africa's Hunter-gatherers Elucidates Human Variation and Ancient Interbreeding. University of Pennsylvania, n.d. Web. 12 Sept <
Tishkoff, Sarah, Joshua Akey, and Kun Zhang. "TEACHING ABOUT EVOLUTION AND THE NATURE OF SCIENCE." Teaching About Evolution and the Nature of Science. University of Pennsylvania, n.d. Web. 12 Sept
Freeman, Scott. "Evolution." Biological Science. 4th ed. Vol. 2nd. N.p.: n.p., n.d. N. pag. Print.