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Distribution of subsets of blood monocytic cells throughout life

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1 Distribution of subsets of blood monocytic cells throughout life
Daniela Damasceno, MSc, Cristina Teodosio, PhD, Wouter B.L. van den Bossche, MD, Martín Perez-Andres, PhD, Sonia Arriba- Méndez, MD, PhD, Luis Muñoz-Bellvis, MD, PhD, Alfonso Romero, MD, PhD, Juan F. Blanco, MD, PhD, Ana Remesal, MD, PhD, Noemi Puig, MD, PhD, Sergio Matarraz, PhD, José Luis Vicente-Villardón, PhD, Jacques J.M. van Dongen, MD, PhD, Julia Almeida, MD, PhD, Alberto Orfao, MD, PhD  Journal of Allergy and Clinical Immunology  DOI: /j.jaci Copyright © 2019 The Authors Terms and Conditions

2 Fig 1 Distribution of different subsets of circulating monocytes in CB and peripheral blood samples from healthy subjects through life. *P < .05 versus CB. #P < .05 versus subjects aged 30 or more to less than 50 years. +P < .05 versus newborns. NB, Newborns. Journal of Allergy and Clinical Immunology DOI: ( /j.jaci ) Copyright © 2019 The Authors Terms and Conditions

3 Fig 2 Relative distribution of different subsets of monocytes in adult blood versus paired BM and paired lymph node and spleen samples. A-E, *P < .05 versus blood. #P < .05 versus lymph nodes. F-J, Multidimensional representations of distinct monocyte cell subsets in different tissues. P > .05 for comparison of the 2 blood sample groups for all monocyte subsets. Journal of Allergy and Clinical Immunology DOI: ( /j.jaci ) Copyright © 2019 The Authors Terms and Conditions

4 Fig E1 Identification of different subsets of circulating monocytes in representative peripheral blood and BM samples from a healthy donor. Journal of Allergy and Clinical Immunology DOI: ( /j.jaci ) Copyright © 2019 The Authors Terms and Conditions

5 Fig E2 Comparison between the phenotypic profile of the different subsets of monocytic cells in BM, lymph node, and spleen versus blood. Journal of Allergy and Clinical Immunology DOI: ( /j.jaci ) Copyright © 2019 The Authors Terms and Conditions


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