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Dose-response curves and images for confirmed screening hits.

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Presentation on theme: "Dose-response curves and images for confirmed screening hits."— Presentation transcript:

1 Dose-response curves and images for confirmed screening hits.
Dose-response curves and images for confirmed screening hits. (A-F) Treatment with the NMDA receptor antagonist ifenprodil (B, 5 µM), the myosin inhibitor blebbistatin (C, 5 µM), the smooth muscle relaxant alverine citrate (D, 5 µM), or the long chain fatty acid pentadecanoic acid (E, 5 µM) all increased measures of neurite growth compared to DMSO treated controls (A), whereas the plant-derived natural diterpene triptolide (F, 1 µM) reduces neurite outgrowth without affecting cell number. Scale bar: 50 µm. Data are mean±s.d., n=6 wells (mean, 244 cells/well). Sean P. Sherman, and Anne G. Bang Dis. Model. Mech. 2018;11:dmm031906 © Published by The Company of Biologists Ltd

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