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Pancreatic β-cell proliferation.
Pancreatic β-cell proliferation. Sections were immunostained for Ki67 (red), insulin (green), and DAPI (blue) (A). The arrows point at Ki67+ cells. Scale bars, 100 μm. Mean±SEM percentage of Ki67+ cells/insulin+ and DAPI+ cells (B). Scale bars, 100 μm. *p<0.05 versus control; †p<0.05 vs Ex-4; §p<0.05 vs BM-CM. BM-CM, bone marrow-derived mesenchymal stem cells; DMEM, Dulbecco's modified Eagle's medium; Ex-4, exendin-4; SHED-CM, conditioned medium from human exfoliated deciduous teeth. Takako Izumoto-Akita et al. BMJ Open Diab Res Care 2015;3:e000128 ©2015 by American Diabetes Association
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