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Stephen A. Harrison  Clinical Gastroenterology and Hepatology 

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Presentation on theme: "Stephen A. Harrison  Clinical Gastroenterology and Hepatology "— Presentation transcript:

1 Insulin Resistance Among Patients With Chronic Hepatitis C: Etiology and Impact on Treatment 
Stephen A. Harrison  Clinical Gastroenterology and Hepatology  Volume 6, Issue 8, Pages (August 2008) DOI: /j.cgh Copyright © 2008 AGA Institute Terms and Conditions

2 Figure 1 Insulin resistance, hepatic steatosis, and advanced fibrosis/cirrhosis. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions

3 Figure 2 Proposed molecular pathways involved in the development of insulin resistance in patients with hepatitis C. aRecent evidence indicates that leptin and adiponectin do not account for the increased insulin resistance found in patients with CHC.53 Additional studies are required to confirm the role of adipocytokines in patients with chronic hepatitis. FAS, fatty acid synthetase; MTP, microsomal triglyceride transfer protein; PP2Ac, protein phosphatase 2Ac; SREBP-1, sterol response element-binding protein-1. Clinical Gastroenterology and Hepatology 2008 6, DOI: ( /j.cgh ) Copyright © 2008 AGA Institute Terms and Conditions


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