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Figure 2 Domain/structural organization of mTOR protein with the positions of the mutations indicated Domain/structural organization of mTOR protein with.

Published byMauno Rantanen Modified over 5 years ago

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Presentation on theme: "Figure 2 Domain/structural organization of mTOR protein with the positions of the mutations indicated Domain/structural organization of mTOR protein with."— Presentation transcript:

1 Figure 2 Domain/structural organization of mTOR protein with the positions of the mutations indicated Domain/structural organization of mTOR protein with the positions of the mutations indicated In black: germline mutations; in blue: somatic mutations; in bold: recurrent mutations. Structural domains are composed of HEAT (huntingtin, elongation factor 3, protein phosphatase 2A, and TOR1) repeats; FAT (FRAP, ATM, TRRAP) domain; FRB (FKBP12-rapamycin binding) domain; kinase domain; and FATC (FAT C-terminal) domain. Rikke S. Møller et al. Neurol Genet 2016;2:e118 © 2016 American Academy of Neurology

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