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Risk Estimation in Type 2 Myocardial Infarction and Myocardial Injury: The TARRACO Risk Score  German Cediel, MD, PhD, Yader Sandoval, MD, Anne Sexter,

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Presentation on theme: "Risk Estimation in Type 2 Myocardial Infarction and Myocardial Injury: The TARRACO Risk Score  German Cediel, MD, PhD, Yader Sandoval, MD, Anne Sexter,"— Presentation transcript:

1 Risk Estimation in Type 2 Myocardial Infarction and Myocardial Injury: The TARRACO Risk Score 
German Cediel, MD, PhD, Yader Sandoval, MD, Anne Sexter, MPH, Anna Carrasquer, MD, Maribel González-del-Hoyo, MD, Gil Bonet, MD, Carme Boqué, MD, PhD, Karen Schulz, DC, Stephen W. Smith, MD, Antoni Bayes-Genis, MD, PhD, Fred S. Apple, PhD, Alfredo Bardaji, MD, PhD  The American Journal of Medicine  Volume 132, Issue 2, Pages (February 2019) DOI: /j.amjmed Copyright © Terms and Conditions

2 Figure 1 Flowchart of patient selection for the 2 study cohorts. MI = myocardial infarction. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © Terms and Conditions

3 Figure 2 Derivation of the TARRACO Risk Score, based on a stepwise multivariable regression analysis, for predicting the risk of major adverse cardiovascular events among patients with type 2 myocardial infarction or myocardial injury. (Left, upper panel) First, the odds ratio for each variable was rounded to an integer, then these integers were assigned to each variable (1 to 3 points each). The total scores (maximum = 13) were divided into 2 risk categories, (left, lower panel) low risk (0 to 6 points) and high risk (7 to 13 points). (Right) Kaplan-Meier analysis of 180-day major adverse cardiovascular events and mortality showed significantly higher rates of major adverse cardiovascular events in the high-risk (gold) group compared with the low-risk (blue) group (derivation cohort). MACE = major adverse cardiovascular events. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © Terms and Conditions

4 Figure 3 Derivation cohort calibration plot. The derivation cohort was divided into 9 groups of predicted probability of major adverse cardiovascular events. Subsequently, calibration was assessed by plotting the predicted probability of major adverse cardiovascular events against the observed frequency of major adverse cardiovascular events. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © Terms and Conditions

5 Figure 4 Kaplan-Meier curves depict the incidence of major adverse cardiovascular events, according to risk categories, in the external validation cohort. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © Terms and Conditions

6 Figure 5 The TARRACO Risk Scores increased with increasing major adverse cardiovascular events incidence. The percentages of major adverse cardiovascular events observed in subgroups based on TARRACO Risk Scores are shown for the derivation (blue) and validation (gold) cohorts. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © Terms and Conditions

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