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Effects of estradiol supplementation during the luteal phase of in vitro fertilization cycles: a meta-analysis Byung Chul Jee, M.D., Chang Suk Suh, M.D., Seok Hyun Kim, M.D., Yong Beom Kim, M.D., Shin Yong Moon, M.D. Fertility and Sterility Volume 93, Issue 2, Pages (January 2010) DOI: /j.fertnstert Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions
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Figure 1 A forest plot demonstrates no benefit of estrogen supplement during luteal phase of IVF cycles using GnRH agonist (top) or antagonist (bottom) in terms of clinical pregnancy rate (PR) per patient. Random effect model was used, because the included studies had a substantial heterogeneity regarding dosage or route of medication and treatment duration. No publication bias was detected by the Begg-Mazumdar test in the studies using GnRH agonist. CI = confidence interval; RR = relative risk. Fertility and Sterility , DOI: ( /j.fertnstert ) Copyright © 2010 American Society for Reproductive Medicine Terms and Conditions
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