1. Reversibility of insulitis after shut-off of Tag expression.
Reversibility of insulitis after shut-off of Tag expression. Double-transgenic RIP7-rtTA × tet-Tag mice were treated with dox between 3 and 8 weeks of age. Pancreas histology was analyzed at the indicated time points after dox removal. The number of islets with insulitis is expressed as a percent of the combined total islet number in 3–4 mice analyzed at each time point (except for the 6-week time point, at which time 10 mice were scored) .
Irina Berkovich, and Shimon Efrat Diabetes 2001;50:
©2001 by American Diabetes Association