Presentation is loading. Please wait.

Presentation is loading. Please wait.

Deletion of Sox2 in adult mice inhibits incisor regeneration.

Published byEustacia Burns Modified over 5 years ago

Similar presentations

Presentation on theme: "Deletion of Sox2 in adult mice inhibits incisor regeneration."— Presentation transcript:

1 Deletion of Sox2 in adult mice inhibits incisor regeneration.
Deletion of Sox2 in adult mice inhibits incisor regeneration. (A) Tamoxifen treatment, tooth length reduction and histological analysis time line in Sox2F/F control and Rosa26Cre-ERT/Sox2F/F mice. (B) Images of P29 and P34 mouse incisors after tamoxifen treatment and cutting of the left lower incisor. First column: mouse incisors after cutting half of the left lower incisor. Second column: mouse incisors 5 days after shortening. Third column: microcomputed tomography (μCT) analysis of shortened incisors after 5 days of recovery. Fourth column: Sox2 expression visualized by immunofluorescence (IF) in tamoxifen-treated Rosa26CreERT/Sox2F/F and control mice. (C) Quantification data (mean±s.e.m.) of the relative growth rate of the shortened incisor in Sox2F/F and Rosa26CreERT /Sox2F/F mice after treatment with tamoxifen. Scale bars: 5 mm (μCT images); 100 µm (IF images). Zhao Sun et al. Development 2016;143: © Published by The Company of Biologists Ltd

Download ppt "Deletion of Sox2 in adult mice inhibits incisor regeneration."

Similar presentations

Mitochondria localize to both the front and the rear of neutrophils.

Mitochondria localize to both the front and the rear of neutrophils.
Sec1p requires Boi1/2p for proper localization.

Sec1p requires Boi1/2p for proper localization.
Fig. 1. BCAS1 expression identifies newly generated oligodendrocytes.

Fig. 1. BCAS1 expression identifies newly generated oligodendrocytes.
Histological changes in mouse colons after DSS treatment.

Histological changes in mouse colons after DSS treatment.
The pathophysiological processes linked to kidney disease.

The pathophysiological processes linked to kidney disease.
Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.
Fig. 5. Differentiated cells sort to the outer layer, regardless of E- or N-cadherin status.Wildtype and mutant ES cells were distinguished by GFP expression.

Fig. 5. Differentiated cells sort to the outer layer, regardless of E- or N-cadherin status.Wildtype and mutant ES cells were distinguished by GFP expression.
Differential Cre-ERT activity and PTEN deletion in endometrial epithelial and stromal compartments. Differential Cre-ERT activity and PTEN deletion in.

Differential Cre-ERT activity and PTEN deletion in endometrial epithelial and stromal compartments. Differential Cre-ERT activity and PTEN deletion in.
Fig. 2. abu/pqn genes are expressed in the pharyngeal cuticle

Fig. 2. abu/pqn genes are expressed in the pharyngeal cuticle
Fig. 4. BMP and nodal induce invasion of metastatic and radial growth phase melanoma cells in human epidermal skin reconstructs. BMP and nodal induce invasion.

Fig. 4. BMP and nodal induce invasion of metastatic and radial growth phase melanoma cells in human epidermal skin reconstructs. BMP and nodal induce invasion.
Smo deficiency in the renal stroma is dependent on GLI3R.

Smo deficiency in the renal stroma is dependent on GLI3R.
Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.

Inflammation is associated with increased basal-cell plasticity in the Nkx3.1 mutant prostate. Inflammation is associated with increased basal-cell plasticity.
Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. (A,B)

Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. (A,B)
Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.

Fig. 3. Inactivation of the Wnt/β-catenin signaling pathway inhibited cell proliferation and induced apoptosis in A549 and SPC-A-1 cells. Inactivation.
Fig. 1. Morphological and growth characterization of hBMCs and hPDCs

Fig. 1. Morphological and growth characterization of hBMCs and hPDCs
Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.

Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse myocardium. Expression of tomoregulin-1 in wild-type and cardiac hypertrophy mouse.
Characterization of Col1a1FRT-STOP-FRT-Cre-ER-T2 mice.

Characterization of Col1a1FRT-STOP-FRT-Cre-ER-T2 mice.
TWEAK downregulates SIRT3 in cultured tubular cells and this is prevented by crotonate. TWEAK downregulates SIRT3 in cultured tubular cells and this is.

TWEAK downregulates SIRT3 in cultured tubular cells and this is prevented by crotonate. TWEAK downregulates SIRT3 in cultured tubular cells and this is.
The initial targeting of Sec61b mRNA to the ER is partially dependent on ribosomes and translation. The initial targeting of Sec61b mRNA to the ER is partially.

The initial targeting of Sec61b mRNA to the ER is partially dependent on ribosomes and translation. The initial targeting of Sec61b mRNA to the ER is partially.
Effect of 20E on locomotion behavior.

Effect of 20E on locomotion behavior.

Similar presentations

Ads by Google