1. The adjMFC end point is independent of baseline titers.
The adjMFC end point is independent of baseline titers. An illustration of our approach for computing adjMFC. The relationship between baseline titers and (A) MFC or (B) adjMFC in SDY404. Vertical lines separate the bins used for standardization, and the inset table indicates the P value resulting from the test for correlation. Correlation strengths and P values shown were based on Spearman’s rank correlation. Note that in this example, an outlier with high day 0 titer was removed when computing the adjMFC (see Methods).
HIPC-CHI Signatures Project Team, and HIPC-I Consortium Sci. Immunol. 2017;2:eaal4656
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