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The Effect of Oral PC-III on Osteoarthritis and Bone Marrow Lesions

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Presentation on theme: "The Effect of Oral PC-III on Osteoarthritis and Bone Marrow Lesions"— Presentation transcript:

1 The Effect of Oral PC-III on Osteoarthritis and Bone Marrow Lesions
A.J. Kiraly, S. Talic, A. Sun, D.R. Mauerhan, E.N. Hanley, Y. Sun  Osteoarthritis and Cartilage  Volume 25, Pages S313-S314 (April 2017) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1: The articular cartilage and subchondral bone changes between PC-III treated animals and control at 3, 6, 12, 18 months. Osteoarthritis and Cartilage  , S313-S314DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2: Histological analysis of bone marrow lesions in Hartley guinea pigs. A – Graphical representation of average grade assigned based off of grading scale. B – Photo of bone marrow of a control animal at 3 months, C and D are examples of found bone marrow lesions. C – Fibrosis (black arrow). D – Encapsulated (red arrow) and non-encapsulated (black arrow) necrosis. Osteoarthritis and Cartilage  , S313-S314DOI: ( /j.joca ) Copyright © Terms and Conditions


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