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Mutations and aneuploidy

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Presentation on theme: "Mutations and aneuploidy"— Presentation transcript:

1 Mutations and aneuploidy
German Pihan, Stephen J Doxsey  Cancer Cell  Volume 4, Issue 2, Pages (August 2003) DOI: /S (03)

2 Figure 1 Pathways leading to numerical and structural CIN
A: Numerical CIN. B: Structural CIN. See text for more details. Cancer Cell 2003 4, 89-94DOI: ( /S (03) )

3 Figure 2 Enabling effect of structural chromosome instability on gene gains and losses A: Transposition of chromosome material facilitates loss of a TSG. B: Transposition of chromosomal material facilitates gain of OGs or other growth-promoting genes. See text for more details. Cancer Cell 2003 4, 89-94DOI: ( /S (03) )


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